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pearl
1
Magnesium sulphate halves the risk of eclampsia in pre-eclamptic pregnant women without significant adverse effect.
Altman D, Carroli G, Duley L et al. Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial. Lancet. 2002 Jun 1;359(9321):1877-90.
  Daniel Jolley
pearl
1
Use of absorbable sutures for simple laceration repair in the ED results in comparable 3 month cosmetic outcome to non-absorbable sutures.
Tejani C, Sivitz AB, Rosen MD et al. A Comparison of Cosmetic Outcomes of Lacerations on the Extremities and Trunk Using Absorbable Versus Nonabsorbable Sutures. Acad Emerg Med. 2014 Jun 1;21(6):637-43.
  Daniel Jolley
pearl
1
Xenon anaesthesia is feasible and non-inferior to sevoflurane anaesthesia for coronary artery bypass surgery.
Stoppe C, Fahlenkamp AV, Rex S et al. Feasibility and safety of xenon compared with sevoflurane anaesthesia in coronary surgical patients: a randomized controlled pilot study. Br J Anaesth. 2013 Sep 1;111(3):406-16.
  Daniel Jolley
pearl
1
Ondansetron may reduce the analgesic effect of acetaminophen/paracetamol.
Ramirez L, Cros J, Marin B et al. Analgesic interaction between ondansetron and acetaminophen after tonsillectomy in children: The Paratron randomized, controlled trial. Eur J Pain. 2015 May 1;19(5):661-8.
  Daniel Jolley
pearl
1
A Global Rating Scale used for paediatric anaesthesia emergency simulation is a reliable and feasible indicator of readiness for independent practice.
Everett TC, Ng E, Power D et al. The Managing Emergencies in Paediatric Anaesthesia global rating scale is a reliable tool for simulation-based assessment in pediatric anesthesia crisis management. Paediatr Anaesth. 2013 Dec 1;23(12):1117-23.
  Daniel Jolley
pearl
1
Pre-operative nebulised budenoside may improve ventilation pressures and compliance, and reduce the inflammatory response to one-lung ventilation.
Ju NY, Gao H, Huang W et al. Therapeutic effect of inhaled budesonide (Pulmicort(®) Turbuhaler) on the inflammatory response to one-lung ventilation. Anaesthesia. 2014 Jan 1;69(1):14-23.
  Daniel Jolley
summary
1
A brief review of post-operative delirium and post-operative cognitive decline, the possibility that anaesthesia and surgery may contribute (though for which evidence is observational and low quality), and potential methods for detection, quantification and avoidance.
Strøm C, Rasmussen LS, Sieber FE. Should general anaesthesia be avoided in the elderly? Anaesthesia. 2014 Jan 1; 69 Suppl 1 (Suppl 1): 354435-44.
  Daniel Jolley
summary
1
Anaesthesia-related neurotoxicity in the developing brain has been observed in animal models and suggested by observational human trials. Conclusive, quality evidence directing significant practice change is however lacking. Anaesthetists should be aware of the current evidence and future directions of research into this important area.
McCann ME Soriano SG. Perioperative central nervous system injury in neonates. Br J Anaesth. 2012 Dec 1;109 Suppl 1:i60-i67.
  Daniel Jolley
pearl
1
Propofol 1 mg/kg reduces emergence delirium in children, without increasing nausea, vomiting or length of PACU stay, unlike fentanyl 1 mcg/kg.
Kim MS, Moon BE, Kim H et al. Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children. Br J Anaesth. 2013 Feb 1;110(2):274-80.
  Daniel Jolley
summary
1
Four-quadrant transversus abdominis plane block with bilateral posterior TAP catheters for 48 hours provides analgesia equivalent to epidural analgesia in patients having laparoscopic colorectal surgery.
Niraj G, Kelkar A, Hart E et al. Comparison of analgesic efficacy of four-quadrant transversus abdominis plane (TAP) block and continuous posterior TAP analgesia with epidural analgesia in patients undergoing laparoscopic colorectal surgery: an open-label, randomised, non-inferiority trial. Anaesthesia. 2014 Apr 1;69(4):348-55.
  Daniel Jolley