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pearl
1
Dexamethasone 8 mg has equal effect in prolonging single-shot supraclavicular block whether given perineurial or intravenously.
Abdallah FW, Johnson J, Chan V et al. Intravenous Dexamethasone and Perineural Dexamethasone Similarly Prolong the Duration of Analgesia After Supraclavicular Brachial Plexus Block: A Randomized, Triple-Arm, Double-Blind, Placebo-Controlled Trial. Reg Anesth Pain Med. 2015 Mar 1;40(2):125-32.
  Daniel Jolley
pearl
1
Intraoperative intravenous lidocaine improves the quality of recovery following ambulatory laparoscopic surgery.
De GS, Fitzgerald P, Streicher LF et al. Systemic lidocaine to improve postoperative quality of recovery after ambulatory laparoscopic surgery. Anesth. Analg. 2012 Aug 1;115(2):262-7.
  Daniel Jolley
pearl
1
Intrathecal fentanyl synergistically improves labour analgesia when given in combination with bupivacaine.
Kee WD, Khaw KS, Ng FF et al. Synergistic Interaction between Fentanyl and Bupivacaine Given Intrathecally for Labor Analgesia. Anesthesiology. 2014 May 1;120(5):1126-36.
  Daniel Jolley
pearl
1
Pulsed radiofrequency stimulation of the suprascapular nerve improves pain and range of motion in those with adhesive capsulitis.
Wu YT, Ho CW, Chen YL et al. Ultrasound-Guided Pulsed Radiofrequency Stimulation of the Suprascapular Nerve for Adhesive Capsulitis: A Prospective, Randomized, Controlled Trial. Anesth. Analg. 2014 Sep 1;119(3):686-92.
  Daniel Jolley
pearl
1
Peri-operative melatonin may cause small reductions in pre-operative anxiety and post-operative pain.
Andersen LP, Werner MU, Rosenberg J et al. A systematic review of peri-operative melatonin. Anaesthesia. 2014 Oct 1; 69 (10): 1163-71.
  Daniel Jolley
pearl
1
Periarticular infiltration with ropivacaine and ketorolac provides equivalent and likely superior post-op analgesia to intrathecal morphine after THA.
Kuchálik J, Granath B, Ljunggren A et al. Postoperative pain relief after total hip arthroplasty: a randomized, double-blind comparison between intrathecal morphine and local infiltration analgesia. Br J Anaesth. 2013 Nov 1;111(5):793-9.
  Daniel Jolley
comment
1
Despite the statistical significance of this finding, I question the clinical significance and appropriateness – especially in the context of ongoing questions regarding the safety of HES solutions and given there are alternative interventions also shown to reduce symptomatic hypotension in this setting.
Mercier FJ, Diemunsch P, Ducloy-Bouthors AS et al. 6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial‡ Br J Anaesth. 2014 Sep 1; 113 (3): 459-67.
  Daniel Jolley
pearl
1
Hydroxylethyl starch preload before spinal caesarean section significantly reduces symptomatic hypotension when compared with Ringer's lactate.
Mercier FJ, Diemunsch P, Ducloy-Bouthors AS et al. 6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial‡ Br J Anaesth. 2014 Sep 1; 113 (3): 459-67.
  Daniel Jolley
pearl
1
Nitrous oxide exposure increases DNA damage which may be associated with increased risk of wound infection after colorectal surgery.
Chen Y, Liu X, Cheng CH et al. Leukocyte DNA damage and wound infection after nitrous oxide administration: a randomized controlled trial. Anesthesiology. 2013 Jun 1;118(6):1322-31.
  Daniel Jolley
pearl
1
Continuous interscalene block offers analgesic benefits up to 1 week after shoulder surgery when compared with either single-shot block or GA alone.
Salviz EA, Xu D, Frulla A et al. Continuous interscalene block in patients having outpatient rotator cuff repair surgery: a prospective randomized trial. Anesth. Analg. 2013 Dec 1;117(6):1485-92.
  Daniel Jolley