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African health sciences · Dec 2019
Predictors of poor glycemic control in adult with type 2 diabetes in South-Eastern Nigeria.
- Innocent Chidi Anioke, Azubike Nnamdi Ezedigboh, Ogechukwu Calista Dozie-Nwakile, Ikechukwu Johnpaul Chukwu, and Peculiar Ngozi Kalu.
- Clinical Chemistry Unit; Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology, College of Medicine, University of Nigeria Enugu Campus, Nigeria.
- Afr Health Sci. 2019 Dec 1; 19 (4): 281928282819-2828.
BackgroundThe study investigated predictors of poor glycemic control in type 2 diabetes (T2DM).MethodsData on demographics, anthropometric and clinical parameters were collected in a cross-section survey from 140 adults with T2DM, using standard tools/instruments. Glycated hemoglobin (A1C) was assessed as a measure of glycemic control.ResultsMajority (83.3%) had poor glycemic control status of which about 95% constitute the elderly. The elderly (OR= 5.90, 95% Cl: 1.66-20.96) were more likely associated with poor glycemic control than the non-elderly (p = 0.006). Adjustment for significant predictor variables: Age, waist-hip ratio (WHR), Fasting plasma glucose (FPG) and Systolic blood pressure (SBP), although attenuated the odds (OR= 5.00, 95% CI: 1.19-20.96) of poor glycemic control, it still remained significantly (p = 0.028) higher in the elderly. Patients outside tight FPG control significantly (p = 0.001) showed poor glycemic cotrol than those within tight FPG (OR= 17.39, 95%Cl: 5.83-51.90), even with attenuated OR (OR= 10.85, 95%Cl: 3.10-37.96) and (OR=12.08, 95%Cl: 3.64-40.09) when non-significant and significant predictor variables were accounted for, respectively.ConclusionAge, WHR, FPG, and SBP were significantly associated with differences in glycemic control. The elderly and FPG outside tight control showed significantly increased odds of poor glycemic control status.© 2019 Anioke et al.
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