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African health sciences · Dec 2019
Randomized Controlled TrialEffect of removal of AuraOnce™ laryngeal mask in awake or deep anaesthesia: a randomized controlled trial.
- Ronald Ombaka, Vitalis Mung'ayi, David Nekyon, and Samina Mir.
- (Anaesthesia), Department of Anaesthesia, Aga Khan University, East Africa.
- Afr Health Sci. 2019 Dec 1; 19 (4): 2954-2963.
BackgroundThe manufacturer Ambu® recommends that the AuraOnce™ laryngeal mask be removed once the patient is fully awake. Studies have shown benefit in removal of the laryngeal mask airway while a patient is deeply anaesthetized. Current evidence is inconclusive, as to which approach is preferable and safer in adults.Methodsone hundred and sixteen adult patients were randomly assigned to two groups of 58. For the deep arm; The AuraOnce™ laryngeal mask was removed after attaining an end tidal minimum alveolar concentration of Isoflurane of 1.15%. Occurrence of airway complication(s) (One or more of the following; Airway obstruction requiring airway manipulation; Laryngospasm; Desaturation to 90% or less on pulse oximetry) was noted until the subject was fully awake (appropriate response to command) in the post-anaesthesia care unit. For the awake arm; The AuraOnce™ laryngeal mask was removed on attaining an end tidal minimum alveolar concentration of Isoflurane of <0.5% and an appropriate response to command or obtaining appropriate response to command irrespective of end tidal concentration. Occurrence of airway complication(s) in theatre and post anaesthesia care unit was recorded. Time to theatre exit was recorded for both groups.ResultsBaseline demographic characteristics were similar between the groups. More airway complications were encountered in the Deep arm - 13 (22.4%) relative to the Awake arm -5 (8.6%), this was found to be statistically and clinically significant, P value P=0.040, odds ratio 3.0622; 95% CI, 1.0139 to 9.2483.ConclusionThe removal of the AuraOnce™ laryngeal mask while the patient is still deeply anaesthetised is not as safe as or safer than awake removal.© 2019 Ombaka et al.
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