• Mol Nutr Food Res · Sep 2013

    Review

    Curcumin, a potential therapeutic candidate for retinal diseases.

    • Lei-Lei Wang, Yue Sun, Kun Huang, and Ling Zheng.
    • College of Life Sciences, Wuhan University, Wuhan, PR China.
    • Mol Nutr Food Res. 2013 Sep 1; 57 (9): 1557-68.

    AbstractCurcumin, the major extraction of turmeric, has been widely used in many countries for centuries both as a spice and as a medicine. In the last decade, researchers have found the beneficial effects of curcumin on multiple disorders are due to its antioxidative, anti-inflammatory, and antiproliferative properties, as well as its novel function as an inhibitor of histone aectyltransferases. In this review, we summarize the recent progress made on studying the beneficial effects of curcumin on multiple retinal diseases, including diabetic retinopathy, glaucoma, and age-related macular degeneration. Recent clinical trials on the effectiveness of phosphatidylcholine formulated curcumin in treating eye diseases have also shown promising results, making curcumin a potent therapeutic drug candidate for inflammatory and degenerative retinal and eye diseases. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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