• J Coll Physicians Surg Pak · Oct 2020

    Case Reports

    Changes in Serum Protein and Enzyme Levels in Human T Lymphotropic Virus-1-Infected Patient.

    • Amer Abdulrahman Almaiman.
    • Department of Applied Medical Sciences, Community College of Unaizah, Qassim University, Qassim, Saudi Arabia.
    • J Coll Physicians Surg Pak. 2020 Oct 1; 30 (10): 1092-1095.

    AbstractThis study aims to evaluate the changes in serum protein levels in a patient with confirmed human T lymphotropic virus type-1 (HTLV-1) infection. Screening and confirmation tests were performed for HTLV-1, along with an assessment of overall albumin, alpha 1 and 2, and gamma and beta globulin levels, using SAS-3 protein electrophoretic analysis. HTLV-1 positivity was confirmed with enzyme-linked immunosorbent assay (ELISA) and nucleic acid amplification testing (NAT). The biochemical tests or protein levels did not exhibit any changes in HTLV-1 infection, indicating that HTLV-1 results in a rare silent infection that does not result in changes in protein levels at the early stages. To aid early detection of the virus and initiate treatment, a comprehensive investigation at the protein and gene levels should be performed. Key Words: HTLV-1, Serum proteins, SAS-3 electrophoretic analysis.

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