• Jifeng Fang, Hui Dong, and Zihui Li.
• Department of Orthopaedics, Second People's Hospital of Liaocheng, Linqing City, Shandong Province, China.
• J Coll Physicians Surg Pak. 2020 Jan 1; 30 (1): 28-32.

ObjectiveTo compare the clinical efficacy of minimally invasive percutaneous lag screw internal fixation and reconstruction plate in the treatment of unstable pelvic fractures.Study DesignAn experimental study.Place And Duration Of StudyThe Department of Orthopaedics, Second People's Hospital of Liaocheng, Linqing City, China, from January 2016 to March 2018.MethodologyA total of 130 patients with unstable pelvic fracture were randomly divided into group A and group B, with 65 cases in each group. Group A was treated with minimally invasive percutaneous lag screw internal fixation, and group B was treated with reconstruction plate. Clinical efficacy of two groups after treatment was evaluated. Serum alkaline phosphatase (ALP), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), stress hormones cortisol (Cor), angiotensin II (Ang II), and norepinephrine (NE) contents were compared.ResultsAfter treatment, the excellent and good rate in group A was higher than that in group B (p=0.005). At 7 days after the operation, serum ALP level in group A was higher than that in group B (p <0.001), serum TNF-α, CRP, Cor, Ang II, and NE levels were lower in group A than those in group B (all p <0.001).ConclusionCompared with reconstruction plate, minimally invasive percutaneous lag screw internal fixation has better clinical efficacy in patients with unstable pelvic fractures; meanwhile, it can effectively increase serum ALP level, reduce the levels of inflammatory cytokines TNF-α and CRP, and effectively reduce surgical trauma as well as postoperative body stress response.

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