• Med. J. Aust. · Dec 1978

    Clinical Trial Controlled Clinical Trial

    Salicylate sensitivity in children reported to respond to salicylate exclusion.

    • M Fitzsimon, P Holborow, P Berry, and S Latham.
    • Med. J. Aust. 1978 Dec 2; 2 (12): 570-2.

    AbstractTwelve children, aged six to 13 years, whose parents reported an improvement in behavioural problems with use of the Feingold (K-P) diet for an average period of 12 months, were challenge-tested with 40 mg of acetylsalicylic acid in a double-blind, cross-over trial with ascorbic acid as a placebo. The children were tested within three hours of ingestion of either the experimental or placebo tablet with a battery of psychological and neurological tests, and were rated by a parent on an enlarged Conners' Parent-Teacher Questionnaire for four days after the ingestion of the tablet. It was found that significance was reached in tests of general cognitive capacity, line walking and the "finger-to-nose" tests, as well as increased disturbance in sleep patterns in these children.

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