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- Jennifer C Munoz Pareja, Kristen Keeley, Ann-Christine Duhaime, and Carter P Dodge.
- Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, 32610, USA. jennifermunozp@peds.ufl.edu.
- Methods Mol. Biol. 2016 Jan 1; 1462: 345-56.
AbstractThe brain has different responses to traumatic injury as a function of its developmental stage. As a model of injury to the immature brain, the piglet shares numerous similarities in regards to morphology and neurodevelopmental sequence compared to humans. This chapter describes a piglet scaled focal contusion model of traumatic brain injury that accounts for the changes in mass and morphology of the brain as it matures, facilitating the study of age-dependent differences in response to a comparable mechanical trauma.
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