• Shinya Matsushima, Minoru Yoshida, Hitoshi Yokoyama, Yosuke Watanabe, Hidetaka Onodera, Haruaki Wakatake, Hiroki Saito, Masahiko Kimura, and Shigeki Shibata.
• Department of Rehabilitation Medicine, St. Marianna University, School of Medicine, Yokohama City Seibu Hospital, Yokohama, Kanagawa, Japan.
• Nutrition. 2021 Nov 1; 91-92: 111407.

ObjectivesThis study aimed to examine the effects of protein intake on physical performance in critically ill adult patients admitted to the intensive care unit (ICU).MethodsThis was a retrospective cohort study of adult patients mechanically ventilated over 48 h in the ICU who were classified into two groups based on the amount of protein intake: >1.0 g/kg/d (high-protein group) or <1.0 g/kg/d (low-protein group). After adjustment for possible confounding factors with propensity score matching, we compared muscle strength at the time of ICU discharge and the rate of recovery to independent walking between the two groups.ResultsOne-to-one propensity score matching created 20 pairs. The high-protein group had significantly higher muscle strength than the low-protein group at the time of discharge from the ICU. In addition, the rate of recovery to independent walking before hospital discharge was higher in the high-protein group than the low-protein group (16 of 20 patients [80%] vs. 8 of 20 patients [40%]; P = 0.032).ConclusionsOur findings indicate that a sufficient amount of protein intake may lead to a higher rate of recovery to independent walking before discharge from the hospital in critically ill patients admitted to the ICU. This finding is likely related to preserved muscle strength at the time of ICU discharge.Copyright © 2021 Elsevier Inc. All rights reserved.

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