• Vilk Janne da Silva Barros, Juliana Soares Severo, Pedro Henrique Moraes Mendes, Alda Cássia Alves da Silva, Kelly Beatriz Vieira de Oliveira, José Miguel Luz Parente, Murilo Moura Lima, Emídio Marques Matos Neto, Armênio Aguiar Dos Santos, and Moisés Tolentino Bento da Silva.
• Graduate Program in Food and Nutrition, Federal University of Piauí, Teresina, PI, Brazil.
• Nutrition. 2021 Nov 1; 91-92: 111457111457.

ObjectivesIn this review, we systematically assess whether dietary interventions are effective in attenuating inflammatory biomarkers in IBDs based on clinical trials available in the literature.Research Methods & ProceduresThis review was conducted in accordance with the guidelines of the PRISMA. We used the PubMed and SciVerse Scopus databases and the Cochrane collaboration tool to assess the risk of bias in clinical trials. The PICO (patient, intervention, comparison, and outcomes) strategy was used, with the descriptors: "Inflammatory bowel disease", "Crohn's disease", "cd", "ibd", "ulcerative colitis", "uc", "Diet", "Diet Habits", "Feeding", "Nutrients", "Food Intake", "Dietary patterns", "Inflammations", "Inflammation", "acute-phase proteins", "C-reactive protein", "interleukins", "tumor necrosis factor-alpha" and "inflammatory response". There is no conflict of interest.Data AnalysisFifteen studies were included, with a total of 627 participants. Of the total studies included, seven showed a reduction in some inflammatory markers in response to dietary interventions. This review was registered with the PROSPERO platform under number: CRD42021235150.ConclusionsThe results presented in this review reveal that dietary intervention with specific characteristics may be important during the treatment of the inflammatory process in patients with IBDs.Copyright © 2021 Elsevier Inc. All rights reserved.

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