• Norosoa Julie Zafindraibe, Zely Arivelo Randriamanantany, Davidra Hendriso Rajaonatahina, Ramamonjisoa Andriamahenina, and Andry Rasamindrakotroka.
• University center hospital of Antananarivo, Para clinic unit of immunology, Antananarivo, Madagascar.
• Afr Health Sci. 2014 Jun 1; 14 (2): 384-9.

IntroductionThe diagnosis of post streptococcal diseases is usually confirmed by immunological tests. Only the antistreptolysin O is usually prescribed by physician. This study aimed to describe the current practice of these requests in Antananarivo.MethodsIt was a retrospective and descriptive study conducted at the Para clinic Unit of Immunology at the University Center Hospital of Antananarivo. We analyzed all requests during seven years, from January 2003 to December 2009. We looked at age, gender, and clinical symptoms which led to the request and the result for each request.ResultsWe retained 4143 requests for antistreptolysin O titration in our study. The mean age of the study participants was 32.9 years with 18.3% of participants being less than 15 years old. The main symptoms leading to the request of this analysis were rheumatologic (41%), followed by neurological (13.9%) and cardiologic symptoms (8.5%) and 19.4% were prescribed for various symptoms. Only 15% of all requests had a value more than 200 U/ml.ConclusionOur study found that in most of requests, ASO titre levels were not significant.

21 keywords...

hide…