• African health sciences · Jun 2014

    Comparative Study

    Liver enzymes and psychological well-being response to aerobic exercise training in patients with chronic hepatitis C.

    • Shehab M Abd El-Kader, Osama H Al-Jiffri, and Fadwa M Al-Shreef.
    • Department of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University.
    • Afr Health Sci. 2014 Jun 1; 14 (2): 414-9.

    BackgroundChronic hepatitis C (CHC) is a medical condition that has broad implications for a person's physical and psychological health.ObjectiveThe aim of this study was to detect changes in liver enzymes and psychological well-being in response to aerobic exercise training in patients with CHC.Material And MethodsFifty CHC patients were included in two equal groups. The first group (A) received aerobic exercise training in addition to their regular medical treatment. The second group (B) received no training and only has their regular medical treatment. The program consisted of three sessions per week for three months.ResultsThere was a significant decrease in mean values of Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Gamma - Glutamyltransferase (GGT), Beck Depression Inventory (BDI ) & Profile of Mood States(POMS) and increase in Rosenberg Self-Esteem Scale (RSES) in group (A) after treatments, but the changes in group (B) were not significant. Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) at the end of the study.ConclusionAerobic exercise training improves hepatic enzymes and psychological well-being in patients with chronic hepatitis C.

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