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- Marko Boban.
- 1Department of Cardiology, Sestre milosrdnice University Hospital Center; 2Faculty of Dental Medicine and Health, University of Osijek; 3Faculty of Medicine, University of Rijeka; 4Faculty of Medicine, University of Osijek.
- Acta Clin Croat. 2019 Nov 1; 58 (Suppl 2): 60-63.
AbstractThe leading cause of death in patients with prostate cancer are cardiovascular diseases. Androgen deprivation therapy is the mainstay of treatment in prostate cancers. The latter has numerous perplexed disadvantaging effects to cardiovascular health. ADT alternates the metabolic profile, insulin resistance and glucose metabolism, causes loss of lean body mass, an increase in adipose tissue, obesity, worsening of atherosclerosis and heart failure. It is important to point out that prostate cancer survivors have increased prevalence of coronary artery disease, cerebrovascular stroke, myocardial infarctions and cardiovascular mortality. Due to these reasons particular care on prevention and treatment of cardiovascular diseases should become a standard of care in patients with prostate cancer.
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