• J Coll Physicians Surg Pak · Jan 2022

    The Relationship of LDH and Hematological Parameters with Ischemic Volume and Prognosis in Cerebrovascular Disease.

    • Tufan Alatlı, Salih Kocaoglu, and Emrah Akay.
    • Department of Emergency, Faculty of Medicine, Balikesir University, Balikesir, Turkey.
    • J Coll Physicians Surg Pak. 2022 Jan 1; 32 (1): 42-45.

    ObjectiveTo determine whether lactate dehydrogenase (LDH), platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR) values can be used as a prediction for their relationship with stroke volume (SV) and for in-hospital mortality in stroke patients in Emergency Department (ED).Study DesignAnalytical study.Place And Duration Of StudyBalikesir University, Turkey from 24/03/2021 to 30/06/2021.MethodologyPatients aged 18 years or older, diagnosed with stroke in ED, were included in the study. Stroke volumes were calculated from diffusion-weighted images (DWi) with 3D slicer software using image-based semi-automatic and manual segmentation methods.ResultsOf the 265 patients, 128 (48.3%) were males. SV was significantly higher in the non-survivor group than in the survivor group (p=0.007). NLR was significantly higher in the non-survivor group than in the survivor group (p=0.018).ConclusionThe ratios of NLR and SV stand out as practical parameters for the estimation of mortality, prognosis, and management of patients diagnosed with acute stroke. Taking into account, these parameters in the diagnosis process and prognosis management in EDs will provide convenience. Key Words: Ischemia, NLR, Stroke volume, Cerebrovasular accident, Prognosis.

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