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J Coll Physicians Surg Pak · Jan 2022
Case ReportsSuccessful Pregnancy Outcome in a Lady with Polyglandular Autoimmune Syndrome Type II.
- Munazzah Rafique and Devjani das.
- Department of Obstetrics and Gynaecology, Wrexham Maelar Hospital, Betsi Cadwaladr University Health Board, North Wales, United Kingdom.
- J Coll Physicians Surg Pak. 2022 Jan 1; 32 (1): 102-104.
AbstractWe report a case of a lady who had polyglandular autoimmune syndrome type II (hypothyroidism, Addison's disease, vitiligo), who completed a successful pregnancy. Addison's disease (AD) was confirmed by the presence of anti-adrenal antibodies and hyponatremia. The patient had pre-pregnancy counselling about the need of antepartum, intrapartum and postpartum steroids. The pregnancy was managed with endocrinologist and obstetrician inputs, and appropriate follow-ups. Her pregnancy was completed with no complications. Labour was complicated by hyponatremia, secondary to nausea and vomiting that needed anaesthesia consultation. The patient delivered by vaginal delivery with no perinatal or early neonatal complications. The fetal growth was at 90th centile. Management in pregnancy, labour and postnatal period requires multidisciplinary care by the endocrinologist, obstetrician, midwife, anaesthetist and neonatologist. Key Words: Addison's disease, Hypothyroidism, Hyponatremia, Labour, Pregnancy.
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