• Jelena Mirnić, Milanko Đurić, Nađa Nikolić, Tanja Veljović, Ivana Gušić, Đorđe Petrović, and Jelena Milašin.
• 1University of Novi Sad, Faculty of Medicine, Department of Periodontology and Oral Medicine, Novi Sad, Serbia; 2Dentistry Clinic, Novi Sad, Serbia; 3Department of Human Genetics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia.
• Acta Clin Croat. 2022 Feb 1; 60 (3): 406-414.

AbstractChronic periodontitis is a common complication in diabetes. The aim of this study was to evaluate some clinical and microbiological parameters in controlled and uncontrolled type 2 diabetes mellitus (type 2 DM) patients compared to non-diabetic (NDM) individuals, as well as to assess the effect of non-surgical periodontal therapy on these parameters. The study was performed in 61 type 2 DM patients with periodontitis (group 1A: 29 patients having achieved good metabolic control, HbA1c <7%; group 1B: 32 patients with poor metabolic control, HbA1c ≥7%), and 31 NDM individuals suffering from periodontitis. Periodontal indices (plaque index, PI; gingival index, GI; probing pocket depth, PPD; and clinical attachment level, CAL) were measured and subgingival plaque samples were analyzed using polymerase chain reaction prior to treatment initiation and 3 months post-treatment. The results recorded on the majority of measured parameters indicated that differences in treatment success achieved in the three treatment groups were not statistically significant (∆PI p=0.646; ∆GI p=0.303; and ∆CAL p=0.233). Likewise, comparison of the effectiveness in microorganism reduction revealed no significant differences between DM groups and NDM patients. Therefore, study results supported the hypothesis that periodontal therapy outcome was unaffected by the level of glycemic control in patients with diabetes.

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