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Preventive medicine · Jul 2012
Making preventive medicine more personalized: implications for exercise-related research.
- Thomas W Buford and Marco Pahor.
- Department of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, FL 32611, USA. tbuford@ufl.edu
- Prev Med. 2012 Jul 1; 55 (1): 34-6.
ObjectiveThis commentary offers a discussion of the need to consider behavioral interventions such as physical exercise as integral components of personalized medicine.MethodsWe discuss the concept of personalized medicine and review existing evidence of variability in response to exercise training.ResultsWe argue that increased understanding is needed regarding sources of variability in exercise responsiveness, and that such understanding should lead to more tailored, often multimodal interventions.ConclusionStudies of personalized medicine to date have primarily investigated heterogeneity in drug responsiveness; we believe it is time to begin considering preventive strategies such as exercise within a broader scope of personalized care.Copyright © 2012 Elsevier Inc. All rights reserved.
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