• Preventive medicine · Dec 2014

    Review Meta Analysis

    Physical activity and cardiovascular risk factors in children: meta-analysis of randomized clinical trials.

    • Claudia Ciceri Cesa, Graciele Sbruzzi, Rodrigo Antonini Ribeiro, Sandra Mari Barbiero, Rosemary de Oliveira Petkowicz, Bruna Eibel, Natássia Bigolin Machado, Renata das Virgens Marques, Gabriela Tortato, Tiago Jerônimo dos Santos, Carina Leiria, SchaanBeatriz D'AgordBDInstituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia, Avenida Princesa Isabel, 370/3 andar. Porto Alegre, Rio Grande do Sul 90620-000, Brazil; Endocrine Division, Hospital de Clínicas de Porto Alegre, , and Lucia Campos Pellanda.
    • Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia, Avenida Princesa Isabel, 370/3 andar. Porto Alegre, Rio Grande do Sul 90620-000, Brazil. Electronic address: claudia.c.cesa@gmail.com.
    • Prev Med. 2014 Dec 1; 69: 54-62.

    ObjectiveTo assess the effects of physical activity interventions in preventing cardiovascular risk factors in childhood through a systematic review and meta-analysis of randomized clinical trials (RCTs).MethodsA search of online databases (PubMed, EMBASE and Cochrane CENTRAL) was conducted from inception until June 2013. RCTs enrolling children 6-12years old conducted physical activity interventions longer than 6months, assessing their effect on body mass index (BMI), systolic (SBP) and diastolic blood pressure (DBP), total cholesterol (TC) and triglycerides (TG) were included. Data analysis was performed using a random-effects model.ResultsOf 23.091 articles retrieved, 11 RCTs (10.748 subjects) were included. Physical activity interventions were not associated with reductions of BMI [-0.03kg/m(2) (95%CI -0.16, 0.13) I(2) 0%]. However, there was an association between the interventions and reduction of SBP [-1.25mmHg (95%CI -2.47, -0.02) I(2) 0%], DBP [-1.34mmHg (95%CI -2.57, -0.11) I(2) 43%] and TG [-0.09mmol/L (95%CI -0.14, -0.04) I(2) 0%], and increase of TC [0.14mmol/L (95%CI 0.01, 0.27) I(2) 0%].ConclusionAs physical activity intervention programs lasting longer than 6months are associated with reductions in blood pressure levels and triglycerides, they should be considered to be included in prevention programs for cardiovascular diseases in schoolchildren.Copyright © 2014 Elsevier Inc. All rights reserved.

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