• J Coll Physicians Surg Pak · Apr 2022

    Case Reports

    A Rare Presentation of Extramedullary Hematopoiesis: Perirenal Masses.

    • Selahattin Durmaz, Cennet Sahin, Muzaffer Basak, and Sukru Mehmet Erturk.
    • Department of Radiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
    • J Coll Physicians Surg Pak. 2022 Apr 1; 32 (4): S28S30S28-S30.

    AbstractExtramedullary hematopoiesis (EMH) is a physiological compensatory mechanism that develops in response to ineffective or insufficient hematopoiesis. Although the liver and spleen are the most common sites, EMH may occur anywhere in the body. Peri-renal involvement in EMH is quite rare and mimics tumoral lesions. To our knowledge, 12 peri-renal EMH cases have been reported in the literature so far.  A 57-year woman was admitted to our hospital with non-specific abdominal pain. She had a history of chronic renal failure. On physical examination, diffuse abdominal tenderness and mild rigidity were detected. Blood tests revealed bicytopenia and elevated acute phase reactants. On non-contrast abdominal computed tomography (CT) scan, two peri-renal mass lesions of 4.5 cm and 4 cm were detected incidentally on the right side. Tumoral lesions were considered in the differential diagnosis, and magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) were performed. Lesions showed mild hypermetabolic activity (SUVmax: 4,68) on PET-CT images. For the definitive diagnosis, an ultrasound-guided core needle biopsy was performed. The histopathological examination was consistent with EMH. This case aims to highlight the peri-renal involvement of EMH, which mimics renal and peri-renal malignancies.

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