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J Coll Physicians Surg Pak · Apr 2022
Case ReportsFrom Gut to Heart: Extensively Drug-resistant Salmonella typhi with Multi System Involvement.
- Sadaf Sheikh and Umair Javed.
- Department of Emergency Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
- J Coll Physicians Surg Pak. 2022 Apr 1; 32 (4): S37-S38.
AbstractExtensively drug-resistant (XDR) salmonella typhi is a gram-negative bacillus, transmitted by feco-oral route. Its systemic manifestations are protean. Untreated enteric fever carries high morbidity and mortality. Life-threatening complications are mainly extra-intestinal, and include involvement of central nervous system, lungs, liver, and genitourinary system. We report a case of a young girl presenting to a hospital in Karachi with a 1-week history of fever, rigors, abdominal pain, watery diarrhea, nausea, and anorexia. She developed toxic myocarditis, pulmonary edema, septic shock, and coagulopathy. Multi-drug-resistant (MDR) salmonella typhi was isolated from blood cultures. Her symptoms resolved after intravenous antibiotics and she completely recovered. Key Words: Myocarditis, Salmonella typhi, Coagulopathy.
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