• Saudi Med J · Jul 2022

    Clinicopathological features and prevalence of prostate cancer in Aseer, Saudi Arabia.

    • Hassan M Otifi, Osama M S Abdul-Wahab, Mishari H Al-Shyarba, Majed S S Al Fayi, Abdullah H Al Murea, and Elhem Yacoub.
    • From the Department of Pathology (Otifi); from the Department of Surgery (Al-Shyarba), College of Medicine; from the Department of Clinical Laboratory Sciences (Abdul-Wahab, Al Fayi), Faculty of Applied Medical Sciences, King Khalid University, from the Department of Laboratory (Al Murea), Aseer Central Hospital, Abha, Kingdom of Saudi Arabia, and from the Specialized Unit of Mycoplasmas, Laboratory of Molecular Microbiology, Vaccinology, and Biotechnology Development (Yacoub), Institut Pasteur de Tunis, University of Tunis El-Manar, Tunis, Tunisia.
    • Saudi Med J. 2022 Jul 1; 43 (7): 755759755-759.

    ObjectivesTo determine the prevalence and characterize prostate cancer (PC) cases in Aseer, Saudi Arabia.MethodsThis study involved 883 patients who consulted physicians in Aseer Central Hospital, Abha, Saudi Arabia, for prostate issues between the years 2008-2018. All patients underwent digital rectal examination and measurement of their serum prostate-specific antigen levels. For patients who presented abnormal digital rectal examination findings and elevated prostate-specific antigen levels, prostate biopsies were recommended. Specimens were histopathologically examined to differentiate between malignant and benign tumors.ResultsAmong the 883 included patients, 132 (15%) underwent a prostate biopsy and were found to have a tumor. Histopathological examination confirmed malignancy (PC) in 77 (8.7%) patients. The absolute majority of the patients diagnosed with PC (96%) were aged >60 years and almost all of them (92%) were found to have a high prostate-specific antigen level of >4 ng/ml.ConclusionProstate cancer appears to be a serious disease in Aseer, Saudi Arabia. Further studies aimed at determining the causes of this type of cancer and understanding its mechanisms are warranted.Copyright: © Saudi Medical Journal.

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