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Preventive medicine · Nov 2022
COVID-19 vaccination is associated with reduced non-COVID in-hospital mortality.
- Jochanan Benbassat, Paul Froom, and Zvi Shimoni.
- Department of Medicine (retired), Hadassah University Hospital Jerusalem, Israel. Electronic address: jochanan.benbassat@gmail.com.
- Prev Med. 2022 Nov 1; 164: 107326107326.
AbstractWe retrieved data on a cohort of medical patients at a regional Israeli hospital. The dependent variable was non-COVID-19 hospital mortality; the independent variables were vaccination status, age, and laboratory data. Serum sodium, age, serum creatinine, and COVID-19 vaccination status were the main independent variables associated with non-COVID-19 mortality. The odds ratio for in-hospital deaths of non-vaccinated patients was 2.01 (1.65-2.44) (unadjusted) and 1.61 (1.29-2.03) after adjustment for the independent variables. This "healthy adherer effect" may confound observational assessments of the clinical efficacy of COVID-19 vaccines.Copyright © 2022 Elsevier Inc. All rights reserved.
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