• Maliha Khalid Khan, Imran Ahmad Khan, and Ammara Liaquat.
• Department of Rehabilitation Sciences, Ali-Ul-Murtaza Muhammad Institute of Medical and Allied Sciences, Multan, Pakistan.
• J Coll Physicians Surg Pak. 2022 Dec 1; 32 (12): 164016431640-1643.

AbstractThis study aimed to assess the synergistic effects of curcumin with and without strengthening exercises in rheumatoid arthritis (RA). Randomised controlled trial study was conducted from May 2021 to December 2021. Ninety patients were randomised into two groups. Group A was treated with strengthening exercises and curcumin. Group B was given curcumin only. Curcumin dosed at 180 mg/day was given orally to both groups. The treatment regimen was distributed as 3 sessions/week; each session lasted 45 minutes for group A. Serological findings and X-rays of the joints were also done for assessment. Pain, morning stiffness, and functional activities were assessed using the WOMAC and NPRS scale at baseline, 12th week, and 24th week. There was higher significant (p<0.000) reduction in quantitative values of RF, ESR and CRP, WOMAC pain, ADLs, and stiffness readings in group A. This study will project to a screening of newer and more effective interventions to treat RA. Key Words: Curcumin, Rheumatoid arthritis, Strengthening exercises.

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