• J Coll Physicians Surg Pak · Dec 2022

    Case Reports

    Primary Hepatic Angiosarcoma: A Rare and Very Aggressive Liver Tumour.

    • Selahattin Durmaz, Muzaffer Basak, Banu Yilmaz Ozguven, Kamile Gulcin Eken, and Sukru Mehmet Erturk.
    • Department of Radiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • J Coll Physicians Surg Pak. 2022 Dec 1; 32 (12): SS209SS211SS209-SS211.

    AbstractPrimary hepatic angiosarcoma (PHA) is a sporadic and aggressive tumour of the liver that originates from mesenchymal cells and represents less than 2% of all primary liver tumours. It is known to be associated with several environmental and industrial carcinogens; however, in 75% of cases, aetiology remains unclear. Patients generally present with nonspecific symptoms and laboratory findings. Imaging has a limited role in the diagnosis.  We herein present a case of a 52-year-old man with a history of hepatitis B-related cirrhosis who was referred to our hospital for liver transplantation assessment. Magnetic resonance imaging (MRI) revealed two small nodular lesions of 5 and 6 mm in segment IV of the liver, categorised as Liver Imaging Reporting and Data System (LI-RADS) category 3. The patient was discussed at a multidisciplinary tumour meeting, and an MRI follow-up in three months was planned. Three months later, MRI depicted a substantial increase in the lesion size measured 8.5 cm. An ultrasound-guided tru-cut biopsy was performed, and the diagnosis of PHA was confirmed by pathology. In this report, we aim to highlight PHA's MRI features and underline this rare entity's rapid and fatal progression.

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