• Zetian Li, Abdul MananHananiHSmell & Taste Clinic, Depatrment of Otrohinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstarsse 74, 01307 Dresden, Germany; Functional Image Processing Laboratory, Department of Radiology, , Hanna Heitmann, Veronica Witte, Kerstin Wirkner, Steffi Riedel-Heller, Arno Villringer, and Thomas Hummel.
• Smell & Taste Clinic, Depatrment of Otrohinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstarsse 74, 01307 Dresden, Germany. Electronic address: zetian.li@mailbox.tu-dresden.de.
• Neuroscience. 2023 May 21; 519: 313731-37.

ObjectiveThe present study aimed to investigate the relationship between olfactory sulcus (OS) depth and olfactory function considering age and gender and to provide normative data on OS depth in a population with normal olfactory function.Materials And MethodsOS depth was obtained using T1 magnetic resonance imaging scans. Participants (mean age ± sd = 57 ± 16 years, ranging from 20 to 80 years) were screened for olfactory function using the Sniffin' Sticks Screening 12 test. They were divided into an olfactory dysfunction group (n = 604) and a normosmia group (n = 493). Participants also completed questionnaires measuring depression, anxiety and quality of life.ResultsThe right OS was deeper than the left side in all age groups. On the left side, women had deeper OS compared with men, exhibiting a higher degree of symmetry in left and right OS depth in women. Variance of olfactory function was largely determined by age, OS depth explained only minor portions of this variance. Normative data for minimum OS depth was 7.55 mm on the left and 8.78 mm on the right for participants aged between 18 and 35 years (n = 144), 6.47 mm on the left and 6.99 mm on the right for those aged 36-55 years (n = 120), and 5.28 mm on the left and 6.19 mm on the right for participants older than 55 years (n = 222).ConclusionConsidering the limited resolution of the presently used T1 weighted MR scans and the nature of the olfactory screening test, OS depth explained only minor portions of the variance of olfactory function, which was largely determined by age. Age-related normative data of OS depth are presented as a reference for future work.Copyright © 2023 IBRO. Published by Elsevier Ltd. All rights reserved.

18 keywords...

hide…