• Olukemi Adekanmbi, Olayinka Ilesanmi, Olusola Idowu, Arinola Esan, Yemi R Raji, Adeola Fowotade, Olubunmi Ogunlade, Adegboyega Akere, Oluwaseun Ololade, Kehinde Ojifinni, Olurotimi Akinola, Akintunde Orunmuyi, Uwom Eze, Victor Akinmoladun, Abiodun Adeoye, Akindele Adebiyi, E Oluwabunmi Olapade-Olaopa, Jesse A Otegbayo, and Kayode Osungbade.
• Department of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
• Afr Health Sci. 2023 Mar 1; 23 (1): 728272-82.

BackgroundData regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available.ObjectivesTo describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients.MethodsA cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors.ResultsMean age was 60.9±16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71±22% and 38±11/minute in non-survivors and 90±7% and 31±7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001).ConclusionMost of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization.© 2023 Adekanmbi O et al.

19 keywords...

hide…