Clopidogrel-induced thrombotic thrombocytopenic purpura: a

African health sciences · Mar 2023

Case Reports

Clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.

Thrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report a case of TTP in a Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. ⋯ Clopidogrel is a cardio-protective anti-platelet drug used in CKD patients at risk of dyspepsia. However, its potential to cause TTP should be recognized and considered in acute kidney injury (AKI) patients previously on clopidogrel.

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- Chidozie N Ndulue, Nonyelum N Jisieike-Onuigbo, Nwabueze J Okwesa, Arinze Anyanor, Bartholomew C Ozuemba, Nwamaka Osakwe, Fidelis Oguejiofor, Hyacinth Eze, Anya Ofia Kalu, and Charles U Odenigbo.
- Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
- Afr Health Sci. 2023 Mar 1; 23 (1): 592595592-595.
AbstractThrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report a case of TTP in a Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. The features of TTP resolved soon after clopidogrel was withdrawn. Clopidogrel is a cardio-protective anti-platelet drug used in CKD patients at risk of dyspepsia. However, its potential to cause TTP should be recognized and considered in acute kidney injury (AKI) patients previously on clopidogrel.© 2023 Ndulue CN et al.

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Clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.

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