• African health sciences · Mar 2023

    A survey of chloroquine use for prevention and treatment of COVID-19 in Nigeria.

    • Adeola Yetunde Olukosi, Muinah Fowora, Adeniyi Kazeem Adeneye, Emelda Chukwu, Oluwagbemiga Aina, Olusola Ajibaye, Ayorinde James, Chidinma Gab-Okafor, Susan Abiodun Holdbrooke, Esther Ngozi Ohihoin, Adesola Zaidat Musa, Olufemi Amoo, Oluyomi Showemimo, Bamgboye Afolabi, Oliver Chukwujekwu Ezechi, and Babatunde Lawal Salako.
    • Biochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
    • Afr Health Sci. 2023 Mar 1; 23 (1): 839283-92.

    BackgroundRampant chloroquine/hydroxychloroquine poisoning in Nigerian hospitals following suggestions of its possible efficacy in the treatment and prevention of the newly emerged COVID-19 disease informed this survey.ObjectivesThe aim of this study was to assess the knowledge, attitude and perception of the Nigerian populace on the use of chloroquine in the COVID-19 pandemic.MethodsThis cross-sectional study was done by administering an electronic questionnaire created using Google Docs, through social media cascade methods including the WhatsApp application software to capture data on chloroquine use between April 20 and June 20, 2020.ResultsSix hundred and twenty-eight people responded to the questionnaire (response rate 99.2%, mean age 41.05 ± 12.3) from the six geopolitical zones in Nigeria with 556 (88.5%) having tertiary level education. Only 21 (3.3%) of the respondents took chloroquine for treatment or prevention. Respondents from the North-west geopolitical zones used chloroquine 5.8 (95% CI: 1.55, 21.52, p=0.02) more times than other zones while the age group 20-29 were 8.8 times more likely to use chloroquine than any other age group (95% CI: 3.53, 21.70, p = 0.00). Female respondents were 2.3 times more likely to use chloroquine than the males (OR 2.26 95% CI: 0.90-5.68; p=0.08) and those in the income bracket of N75,000-99,000, 2.5 times more than other income groups.ConclusionYoung adults, North-western geopolitical zone, and female gender should be target groups for education on rational chloroquine use. The danger of chloroquine overdose should be communicated to the general population in Nigeria.© 2023 Olukosi AY et al.

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