• Elmigdad Abdelgadir Ali Mohamed and Khilood Seddiq Ahmed Mohamed.
• Alghad International Colleges for Applied Medical Sciences, Educational and Academic Affairs.
• Afr Health Sci. 2023 Mar 1; 23 (1): 162216-22.

BackgroundCOVID19 is associated with a number of laboratory characteristics and changes with different levels of prognostic significance. We report changes in lab findings between severe and non-severe COVID-19 in patients that had molecular testing of nasopharyngeal swabs in Khartoum, Sudan.Material And MethodsThis was a descriptive cross-sectional study, conducted from Jan to May 2021. It included 66 preidentified COVID19 patients who attended the isolation center at Jabra Hospital in Khartoum the capital city of Sudan. Participants were enrolled for CBC, D-dimer and C-Reactive Protein testing. Among these participants, 21(31.8%) had severe COVID19 pneumonia.. Data were analysed using SPSS version 24, and the independent sample t-test was used to compare severe and non-sever cases.ResultsThe mean values for all cases showed a mild decrease in Hb (9.53±1.83 g/dl), MCHC (28.3±2.91 g/dl); lymphocytes % (19.8 ±6.82); increased RDW-SD (50.1±5.70 fL), D-dimer (4.2±3.73 µg/ml) and CRP (107.2±61.21 mg/dl). There were significant d/span>differences in the laboratory findings between severe and non-severe COVID-19 cases in total WBCs (p value = .001), lymphocyte % (p value = .000), neutrophil % (p value=.038), RDW-SD (p value = .044), D-dimer (p value = .029) and CRP (p value = .044).ConclusionThe laboratory findings of CBC, D-dimer and CRP provide an essential contribution to predicti COVID-19 severity and prognosis.© 2023 Mohamed EAA et al.

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