• Nutrition · Nov 2023

    Review

    Pathogenesis and treatment of depression: Role of diet in prevention and therapy.

    • Weronika Mrozek, Justyna Socha, Klara Sidorowicz, Aleksandra Skrok, Aleksandra Syrytczyk, Iwona Piątkowska-Chmiel, and Mariola Herbet.
    • Department of Toxicology, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
    • Nutrition. 2023 Nov 1; 115: 112143112143.

    AbstractIn recent years, there has been a significant increase in depression, which is related to, among other things, the COVID-19 pandemic. Depression can be fatal if not treated or if treated inappropriately. Depression is the leading cause of suicide attempts. The disease is multifactorial, and pharmacotherapy often fails to bring satisfactory results. Therefore, increasingly more importance is attached to the natural healing substances and nutrients in food, which can significantly affect the therapy process and prevention of depressive disorders. A proper diet is vital to preventing depression and can be a valuable addition to psychological and pharmacologic treatment. An inadequate diet may reduce the effectiveness of antidepressants or increase their side effects, leading to life-threatening symptoms. This study aimed to review the literature on the pathogenesis of the development and treatment of depression, with particular emphasis on dietary supplements and the role of nutrition in the prevention and treatment of depressive disorders.Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

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