• Farhan Ahmad Majeed, Kamran Raheem, Usama Zafar, Sohail Saqib Chatha, Ahmad Raza, and Arshman Rauf.
• Department of Thoracic Surgery, Combined Military Hospital, Rawalpindi, Pakistan.
• J Coll Physicians Surg Pak. 2023 Sep 1; 33 (9): 106210661062-1066.

ObjectiveTo determine the yield of cervical mediastinoscopy in determining causes of mediastinal lymph node enlargement.Study DesignObservational study. Place and Duration of the Study: CMH Rawalpindi, Lahore and Multan, from January 2010 to December 2021.MethodologyPatients who underwent lymph node biopsy through cervical mediastinoscopy approach were included. Record of the patients including age, gender, clinical presentation, and findings on CT scan chest were noted along with the record of preoperative complications and duration of surgery. Histopathology report was also recorded.ResultsOut of 398 patients, 259 (65%) were males and 139 (35%) were females. Out of 338 patients who were operated for diagnostic purpose, 157 (46%) had tuberculosis and 34 (10.1%) had sarcoidosis. Fifty-two (15.3%) were diagnosed to have malignancy including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), and metastatic carcinoma of unspecified origin. Amongst staging group (n=60), 33 (55%) patients had negative mediastinal disease. Complication rate was 3.8%, including hoarseness of voice in three patients while 2 patients had wound infection requiring intervention.ConclusionCervical mediastinoscopy is a safe and efficacious means of diagnosis in indeterminate mediastinal lymphadenopathy and staging of lung malignancy.Key WordsMediastinoscopy, Lymph nodes, Tuberculosis, Lung cancer, Staging.

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