• Valérian Rivet, Sophie Riviere, Radjiv Goulabchand, Benoît Suzon, Pierrick Henneton, Léo Partouche, Patricia Rullier, QuellecAlain LeALDepartment of Internal Medicine: Multi-Organic Diseases, Saint-Eloi Hospital, University Hospital Center of Montpellier, Montpellier, France; Montpellier University Hospital, Montpellier, France., Amadou Konate, Aurélie Schiffmann, Thierry Vincent, Rahima Ziane, Nicolas Flori, Marie Christine Picot, Ariane Sultan, Alexandre Thibaut Jacques Maria, and Philippe Guilpain.
• Internal Medicine and Immunopathology Departement, Cancer University of Toulouse Oncopole, University Hospital Center of Toulouse, Toulouse, France.
• Nutrition. 2023 Dec 1; 116: 112171112171.

ObjectivesSystemic sclerosis (SSc) can cause malnutrition due to frequent gastrointestinal involvement. However, prevalence of malnutrition in SSc is poorly known. The aim of this study was to evaluate the prevalence of malnutrition in SSc and its potential associations with disease features in patients from a tertiary referral center.MethodsAll patients meeting American College of Rheumatology/European Alliance of Associations for Rheumatology criteria for SSc followed between January 1, 1985, and January 1, 2019, at the Department of Internal Medicine, Saint Eloi University Hospital, were included. Malnutrition was assessed using the 2020 French recommendations for SSc and the malnutrition universal screening tool score. Severe malnutrition was defined via the French Haute Autorité de Santé (National Health Authority) 2007 criteria.ResultsA total of 120 patients were included, with mean age 64 (± 15) y and a female-to-male sex ratio of 5:1. According to 2020 French recommendations, 71 patients (59.2%) were malnourished and 30 (25%) had at least one criterion of severe malnutrition. With the malnutrition universal screening tool score, 41.7%, 20%, and 38.3%, respectively, had low, medium, and high risk of malnutrition. Multivariate analysis revealed the following results: 1) malnutrition was associated with cardiac involvement (P < 0.01); 2) a high malnutrition universal screening tool score was also associated with specific cardiac involvement (P < 0.01); and 3) severe malnutrition was strongly correlated with interincisal distance <35 mm (P = 0.02).ConclusionsMalnutrition affects more than half of SSc patients and is associated with specific cardiac involvement. Interincisal distance <35 mm could be a red flag for severe malnutrition in SSc.Copyright © 2023 Elsevier Inc. All rights reserved.

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