• Gum-Ryeong Park.
• Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Department of Health, Aging & Society, McMaster University, Hamilton, Ontario, Canada. Electronic address: gumryeong.park@utoronto.ca.
• Prev Med. 2024 Apr 1; 181: 107920107920.

PurposeAlthough prior literature documented socioeconomic inequalities in deaths of despair among working age population, it is unclear whether and how (a) the link between socioeconomic status and deaths of despair differs by age (b) each measure of socioeconomic status has independent effects on deaths of despair. This study aims to reduce these knowledge gaps.MethodsUsing data from a large scale nationally representative linked dataset (2011 Canadian Census Health and Environment Cohorts), this study employed Fine-Gray subdistribution hazard models to estimate the link between socioeconomic status and deaths of despair due to suicide, drug overdose, and alcoholic liver disease among working age population (N = 4,076,530). Age stratified analysis was conducted to examine age heterogeneity.ResultsSocioeconomic status, such as housing tenure, employment status, household income, and education level, was associated with deaths of despair among working age population. Age differences in the association between socioeconomic status and deaths of despair were found. While education level was pronounced for deaths of despair for younger adults, a combination of socioeconomic status was significantly associated with deaths of despair for those in late adulthood.ConclusionsSocioeconomic inequalities in deaths of despair are manifest among Canadian working age population. This study lends support the social and health policies aimed at reducing gaps in mortalities.Copyright © 2024 Elsevier Inc. All rights reserved.

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