• Reed M Reynolds, James F Trasher, Bo Yang, Katherine C Henderson, David L Ashley, Emily E Hackworth, Charity A Ntansah, Di Pei, and Lucy Popova.
• Communication Department, University of Massachusetts, Boston, MA, USA. Electronic address: reed.reynolds@umb.edu.
• Prev Med. 2024 Jul 1; 184: 107952107952.

BackgroundThe U.S. Food and Drug Administration is considering a policy to reduce nicotine in cigarettes to non-addictive levels. Although current evidence supports the public-health benefits of a reduced-nicotine policy, almost half of people who smoke (∼ 40%) do not support the policy. This study estimates the factors most strongly associated with support or opposition toward the policy, including tobacco use status, perceived effects of a reduced nicotine policy, trust in the FDA, and psychological distress. The study aims to inform messaging campaigns and policy makers.MethodsData were collected in 2021 with nationally representative samples of U.S. adults (n = 1763). After receiving information about the reduced nicotine policy, participants indicated their beliefs and support for or opposition to the policy, along with other individual difference characteristics. Univariate population parameters and multinomial logistic regression coefficients were estimated.ResultsIn adjusted models, people who formerly or never smoked were less likely to oppose the policy compared to those who currently smoke; people with higher psychological distress and those who believe the policy will promote switching to e-cigarettes were more likely to oppose the policy. In addition, people were more likely to support the policy if they believed it would make quitting easier or that the FDA is trustworthy.ConclusionsEducational campaigns about reduced nicotine policy should expect higher impact by targeting prevalent perceptions and those more strongly associated with policy sentiment. In anticipation of the policy rollout, there may be a critical window to shape public opinion.Copyright © 2024 Elsevier Inc. All rights reserved.

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