• Sean P Heffron, Caron B Rockman, Eugenia Gianos, Yu Guo, and Jeffrey S Berger.
• Department of Medicine, Leon H. Charney Division of Cardiology, New York University Langone Medical Center, New York University School of Medicine, 550 First Avenue, New York, NY, USA. Electronic address: sean.heffron@nyumc.org.
• Prev Med. 2015 Mar 1; 72: 151815-8.

UnlabelledNut consumption has been associated with lower risk of coronary heart disease and all-cause mortality. The association between nut intake and peripheral arterial disease (PAD) is uncertain.ObjectiveWe sought to investigate the association between nut consumption and presence of prevalent PAD in a large cross-sectional sample.MethodsSelf-referred participants at >20,000 US sites who completed a medical and lifestyle questionnaire were evaluated by screening ankle brachial indices for PAD. Multivariable logistic regression analysis was used to estimate odds of PAD in different nut consumption categories.ResultsAmong 3,312,403 individuals, mean age was 63.6 ± 10.6 years and 62.8% were female. There were 219,527 cases of PAD. After multivariable adjustment there was an inverse association of nut intake with PAD. Compared to subjects with consumption of nutsConclusionThese observations suggest the need for more rigorous testing evaluating the role of nuts in PAD prevention.Copyright © 2014 Elsevier Inc. All rights reserved.

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