• Cemile Uyar, Emel Yıldız, Özlem Genç, Öznur Ak, Emel Koçak, Sevil Alkan, Canan Balcı, Pınar Korkmaz, Duru Mıstanoğlu Özatağ, and Halil Aslan.
• From the Department of Infectious Diseases and Clinical Microbiology (Uyar, Ak, Korkmaz, Mıstanoğlu Özatağ, Aslan); from the Department of Anesthesiology and Reanimation (Yıldız); from the Department of Medical Microbiology (Genç), Faculty of Medicine, Kütahya University of Health Sciences, Kütahya, from the Department of Infectious Diseases and Clinical Microbiology (Alkan), Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, and from the Department of Anesthesiology and Reanimation (Balcı), Faculty of Medicine, Ümraniye Education and Research Hospital, Istanbul, Turkey.
• Saudi Med J. 2024 Jun 1; 45 (6): 606616606-616.

ObjectivesTo assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022.MethodsThe evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation-II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, antibiotic use, lymphopenia, and laboratory variables were evaluated. Candida species distribution, antifungal susceptibility in blood culture were determined.ResultsCoronavirus disease-19 was present in 62.8% of cases confirmed candidemia, and these cases were significantly different from COVID-19 negative cases. Significance was found in more intubation, central venous catheter use, parenteral nutrition, and steroid therapy in Group 2. There was no significance with species distribution and associated infection. In total, COVID-19 positive had higher hemoglobin, aspartate aminotransferase, alanine transaminase, and white blood cell levels, which may be associated with the possibility of revealing and controlling candidemia.ConclusionCandida albicans and Candida Parapsilosis (C. parapsilosis) are the species seen in infected COVID-19 patients, while C. parapsilosis and Candida tropicalis are found in non-COVID-19 ones. Risk factors were intubation, parenteral nutrition, central venous catheter, and steroid in the COVID-19 group.Copyright: © Saudi Medical Journal.

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