• Jamilah S AlRahimi, Yasser M Ismail, Noor A Aljubairi, Nawal W Kutob, Ghadi S Bakulka, Ruqayyah A Ahmed, Fatima A Ahmed, and Ali A Haneef.
• From the Department of Cardiology (AlRahimi, Ismail, Ahmed, Haneef); from the Department of Cardiothoracic Surgery (Haneef), King Abdulaziz Medical City, Ministry of National Guard Health Affairs, from King Abdullah International Medical Research Center (AlRahimi, Ismail, Aljubairi, Kutob, Bakulka), from the College of Medicine (AlRahimi); from the College of Applied Medical Sciences (Ismail, Aljubairi, Kutob, Bakulka), King Saud bin Abdulaziz University for Health Sciences, and from the College of Medicine (Ahmed), Batterjee Medical College for Science and Technology, Jeddah, Kingdom of Saudi Arabia.
• Saudi Med J. 2024 Jun 1; 45 (6): 572577572-577.

ObjectivesTo evaluate the relationship between severity of tricuspid regurgitation (TR) and pulmonary hypertension.MethodsCross-sectional study of 118 patients with pulmonary hypertension was carried out at a single center in Jeddah, Saudi Arabia, between 2018-2021. Patients who had pulmonary or tricuspid valves organic diseases, previously undergone tricuspid or pulmonary valve surgeries, had permanent pacemakers or critically ill were excluded.ResultsA high proportion of patients were women (n=100, 85%) and obese (n=57, 48%). Patients with more than mild TR had higher systolic pulmonary artery pressure (sPAP) than those with trivial or mild regurgitation (p<0.001). There was a significant association between severity of TR (p<0.001) and right chambers size (p=0.001). Furthermore, pulmonary artery pressure (PAP) was significantly higher in patients with mild right ventricular impairment (p=0.001).ConclusionIncrease in degree of TR and right atrial size were predictors of elevated sPAP. Our findings highlight the interplay among TR, right heart size, ventricular function, and PAP. Understanding these associations can aid in risk stratification, monitoring disease progression, and potentially guiding treatment in those patients.Copyright: © Saudi Medical Journal.

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