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Case Reports
Efficacy of denosumab treatment for lung metastasis secondary to proximal humerus chondroblastoma.
- Ramy Samargandi, Mathilde Bernard, Elodie Miquelestorena-Standley, and Louis Romée Le Nail.
- From the Department of Orthopedic Surgery and Traumatology (Samargandi, Bernard, Le Nail); from the Department of pathology (Miquelestorena-Standley), Tours Regional University Hospital, Tours, France, and from the Department of Orthopedic Surgery (Samargandi), Faculty of Medicine, University of Jeddah, Jeddah, Kingdom of Saudi Arabia.
- Saudi Med J. 2024 Jun 1; 45 (6): 633638633-638.
AbstractChondroblastoma is a rare benign cartilaginous tumor that accounts for approximately 1% of bone tumors, but it can be associated with lung metastasis in extremely rare cases, leading to a poor prognosis and death. Herein, we report the case of a 19-year-old male patient who presented with an aggressive chondroblastoma of the proximal humerus and bilateral lung metastasis. The patient was treated with wide local resection, partial metastasectomy, and denosumab. Denosumab treatment was effective in controlling metastatic progression and preventing local recurrence.Copyright: © Saudi Medical Journal.
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