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Mayo Clinic proceedings · Jan 2000
Comparative StudyProstatic steroid 5 alpha-reductase, an androgen metabolic gene.
- J K Reichardt.
- Department of Biochemistry and Molecular Biology, USC School of Medicine, Los Angeles, USA.
- Mayo Clin. Proc. 2000 Jan 1; 75 Suppl: S36S39S36-9.
AbstractProstate cancer risk is highest in African Americans, lowest in Asians, and intermediate in Caucasians and Latinos. The data clearly suggest that environmental and genetic factors are involved. Investigation of the genetic factors suggests that allelic variation in the SRD5A2 gene is partially responsible for the striking racial and ethnic variations in risk.
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