• Yigit Duzkoylu, Mesut Ozdedeoglu, Huseyin Kilavuz, Mahmut Kaan Demircioglu, Huseyin Karatay, and Ali Emre Nayci.
• Department of Gastroenterological Surgery, Basaksehir City Hospital, Istanbul, Turkiye.
• J Coll Physicians Surg Pak. 2024 Aug 1; 34 (8): 942947942-947.

ObjectiveTo compare the short-term results of complete mesogastric excision with the conventional surgical technique.Study DesignAn experimental study. Place and Duration of the Study: Department of Gastroenterological Surgery, Health Sciences University, Basaksehir City Hospital, Istanbul, Turkiye, from April to December 2023.MethodologyComparison of short-term results of open total gastrectomy + mesogastrectomy with standard total gastrectomy + D2 lymph node dissection at a tertiary centre in terms of peroperative results, histopathological findings, and postoperative short-term outcomes prospectively, with review of the literature.ResultsA total of 37 patients were included in the study. The groups involved 26 male and 11 female patients. The study group included 14 patients while the control group involved 23 patients. The mean blood loss (mL) was significantly lower and number of metastatic lymph nodes was significantly higher in the study group.ConclusionTotal mesogastric excision is a safe technique which has advantages over conventional D2 gastrectomy in terms of not only peroperative and short-term outcomes, but also disease-free survival. This is the first study from a different population of the world and initial results can contribute to the literature for universalisation.Key WordsComplete mesogastrium excision, D2 lymphadenectomy, Gastric cancer, Gastrectomy, Mesogastrectomy.

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