• Ayca Tuba Dumanli Ozcan, Serhat Ocakli, Ezgi Erkilic, Yasemin Yalniz, Sadettin Er, and Cengiz Ceylan.
• Department of Anaesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkiye.
• J Coll Physicians Surg Pak. 2024 Sep 1; 34 (9): 100910131009-1013.

ObjectiveTo determine the outcome of awake surgery with combined spinal epidural in geriatric colon cancer patients with advanced comorbidity.Study DesignQuasi-experimental study. Place and Duration of the Study: Department of Anaesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkiye, from April 2022 to 2023.MethodologyTwenty-four American Society of Anaesthesiologists (ASA) I-II patients, aged 25-65 years and scheduled for colon cancer surgery were included in this research. All patients were observed preoperatively, at the operation room and at the postoperative surgery service. Spinal anaesthesia was planned for Group I and general anaesthesia for Group II. Ketofol (1:1) was administered to the combined spinal-epidural group, with a Ramsay sedation score of 3 after the spinal block. Epidural analgesia was planned for all patients. Patients' age, gender, weight, comorbidities, ASA risk scores, intraoperative haemodynamic parameters, bleeding amounts, colloid, crystalloid, and blood products were collected.ResultsThere was no significant difference between the demographic characteristics of both anaesthesia groups (p >0.05). The amount of bleeding was statistically lower in Group I than in the general anaesthesia group (p = 0.004). Oral intake, drain withdrawal, mobilisation, discharge times, and costs were similar in all groups (p >0.05).ConclusionThe regional anaesthesia applications facilitate compliance with routine mobilisation, discharge procedures and prevent complications in abdominal surgery and its positive perioperative effects in patients with poor respiratory parameters, poor general condition, and high comorbidity in advanced age.Key WordsRegional anaesthesia, Spinal-epidural, Mobilisation, Pain, Colon cancer.

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