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J Coll Physicians Surg Pak · Oct 2024
Risk Factors for Renal Involvement in Childhood Henoch-Schonlein Purpura (IgA Vasculitis).
- Shuhui Min, Xi Chen, Danfeng Wang, Xiao Lin, and Guan Jiang.
- Department of Dermatology, Affiliated Hospital of Xuzhou Medical University, Jiangsu, China.
- J Coll Physicians Surg Pak. 2024 Oct 1; 34 (10): 125812611258-1261.
AbstractThis study was designed to investigate the risk factors for renal involvement in children with immunoglobulin A (IgA) vasculitis. It is a hospital-based retrospective cohort study with a sample size of 117 children aged ≤16 years with primary IgA vasculitis. Out of 117 patients, 49 (41.9%) developed renal injury. Univariate analysis revealed that age, gastrointestinal bleeding (GIB), time of duration, white blood cell count, D-dimer, and platelet count were all associated with renal injury in the patients with HSP. These variables were included in the multivariate logistic regression analysis. Results showed that elevated D-dimer level, older age, and GIB were independent risk factors for renal damage in patients with IgA vasculitis. Key Words: Henoch-schonlein purpura, Immunoglobulin A vasculitis, Nephritis, D-dimer, Risk factors.
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