• Kenji Takami, Mari Higashiyama, and Shigeyoshi Tsuji.
• Department of Orthopaedic Surgery, Nippon Life Hospital, Osaka, Japan; Psoriasis Center, Nippon Life Hospital, Osaka, Japan. Electronic address: k.takami14@gmail.com.
• Nutrition. 2024 Oct 10; 129: 112595112595.

ObjectiveThe risk of both osteoporosis and sarcopenia is high in inflammatory diseases, but there have been few reports of psoriatic arthritis (PsA). This study aimed to evaluate the rate of sarcopenia and osteoporosis, and the association of sarcopenia with osteoporosis in patients with PsA at our institution.MethodsThe data in this study were extracted from 320 patients with PsA meeting CASPAR criteria diagnosed between January 2010 and December 2021. The 156 patients who had undergone body composition measurements with dual-energy X-ray absorptiometry were included.ResultsOverall, the rate of sarcopenia and presarcopenia were 5.1% and 16.7%. Body mass index (BMI) was significantly lower in the presarcopenia and sarcopenia group. Furthermore, the presarcopenia and sarcopenia group had a significantly lower T-score in all regions. Multivariate analysis of the determinants of T-score for each site showed that SMI was significantly involved for the lumbar spine and the femoral neck, and BMI and rheumatoid factor positivity for the total hip.ConclusionsIn patients with PsA, the rate of sarcopenia was 5.1%. Osteoporosis rates for males and females were 5.7% and 7.5%, respectively. SMI, T-score, and BMI are significantly correlated with each other and should be considered in clinical practice.Copyright © 2024 Elsevier Inc. All rights reserved.

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