• Bull. Exp. Biol. Med. · Dec 2012

    Study of nociceptive flexion reflex in healthy subjects and patients with chronic neuropathic pain syndrome.

    • S A Gordeev, L G Turbina, A A Zus'man, and S I Posokhov.
    • Department of Pathology of Autonomic Nervous System, I. M. Sechenov First Moscow State Medical University, Moscow, Russia. gordeevSA58@mail.ru
    • Bull. Exp. Biol. Med. 2012 Dec 1;154(2):189-91.

    AbstractNociceptive flexion reflex was measured in healthy subjects and patients with chronic neuropathic pain (diabetic distal symmetric sensorimotor polyneuropathy). The study of nociceptive flexion reflex revealed reduction of subjective pain threshold and reflex threshold in patients compared with healthy persons reflecting deficit of descending antinociceptive influences in the CNS.

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