Bulletin of experimental biology and medicine
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Bull. Exp. Biol. Med. · Dec 2012
Study of nociceptive flexion reflex in healthy subjects and patients with chronic neuropathic pain syndrome.
Nociceptive flexion reflex was measured in healthy subjects and patients with chronic neuropathic pain (diabetic distal symmetric sensorimotor polyneuropathy). The study of nociceptive flexion reflex revealed reduction of subjective pain threshold and reflex threshold in patients compared with healthy persons reflecting deficit of descending antinociceptive influences in the CNS.