• Handb Clin Neurol · Jan 2013

    Review Historical Article

    Neuromuscular complications of critical illness.

    • Kurien Koshy and Douglas W Zochodne.
    • Department of Clinical Neurosciences and the Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.
    • Handb Clin Neurol. 2013 Jan 1; 115: 759-80.

    AbstractPatients admitted to intensive care units (ICUs) suffer from a wide range of neurological disorders. Some develop within the ICU rendering weakness and difficulty in weaning patients from ventilator support. ICUAW, or ICU acquired weakness, is a broad term that includes several more specific neuromuscular problems. After exclusion of other causes of weakness, ICUAW includes critical illness polyneuropathy (CIP), first described by Charles Bolton, critical illness myopathy (CIM), and disorders of neuromuscular junction transmission. This chapter reviews the clinical, electrophysiological, and pathological features of these conditions and provides clinicians with approaches toward diagnosing and investigating ICUAW.Copyright © 2013 Elsevier B.V. All rights reserved.

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