• G Natalini, P Facchetti, M A Dicembrini, G Lanza, A Rosano, and A Bernardini.
• Department of Anesthesia, Intensive Care and Emergency, Casa di Cura Poliambulanza, Via Bissolati 57, 25124 Brescia, Italy. giuseppe.natalini@libero.it
• J Clin Anesth. 2001 Sep 1; 13 (6): 436-9.

Study ObjectiveTo quantify the impact on peak airway pressure of pressure-controlled and volume-controlled ventilation during Laryngeal Mask Airway (LMA) use.DesignProspective, crossover clinical study.SettingUniversity-affiliated hospital.Patients32 ASA physical status I and II patients undergoing general anesthesia with the LMA.InterventionsPatients were ventilated for three minutes both with pressure-controlled and volume-controlled ventilation, provided that tidal volume (V(T) ) and inspiratory time (It) were constant.Measurements And Main ResultsThe monitored parameters were electrocardiography, arterial blood pressure, pulse oximetry, capnography, neuromuscular transmission, airway pressure and flow, and concentration of ventilated vapors and gases. The actually delivered V(T) was similar with both types of ventilation (volume-controlled = 0.67 +/- 0.13 lt, pressure-controlled = 0.67 +/- 0.14 lt; p = 0.688). Peak airway pressure was lower during pressure-controlled ventilation (14.6 +/- 3.5 cmH(2)O) than during volume-controlled ventilation (16 +/- 4 cmH(2)O) (p < 0.001). Furthermore, we noted that the higher the airway pressure with volume-controlled ventilation, the greater was the reduction in airway pressure during pressure-controlled ventilation.ConclusionsPressure-controlled rather than volume-controlled ventilation can improve the effectiveness of mechanical ventilation in patients with high airway pressure.

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