• Childs Nerv Syst · Jan 2008

    Case Reports

    Ethylenevinylalcohol copolymer (Onyx-18) used in endovascular treatment of vein of Galen malformation.

    • Anand V Germanwala, Nirav A Vora, Ajith J Thomas, Tudor Jovin, Yakov Gologorsky, and Michael B Horowitz.
    • Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
    • Childs Nerv Syst. 2008 Jan 1; 24 (1): 135-8.

    BackgroundVein of Galen malformations (VGM) are rare congenital arteriovenous fistulas that usually present with heart failure in the neonate. Endovascular treatment options in the past have utilized coils, balloons, and acrylics.Case ReportWe present, for the first time in the literature, a case of an infant with VGM treated initially with staged coil embolizations followed 1 year later by the transarterial and transvenous catheter based injection of Onyx-18 (ethylenevinylalcohol copolymer) in a single treatment session. The fistula was eliminated, and the infant's cardiopulmonary symptoms were improved.

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