• Neuroscience · Nov 2017

    Connectome-scale Functional Intrinsic Connectivity Networks in Macaques.

    • Wei Zhang, Xi Jiang, Shu Zhang, Brittany R Howell, Yu Zhao, Tuo Zhang, Lei Guo, Mar M Sanchez, Xiaoping Hu, and Tianming Liu.
    • Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, Athens, GA, USA.
    • Neuroscience. 2017 Nov 19; 364: 1-14.

    AbstractThere have been extensive studies of intrinsic connectivity networks (ICNs) in the human brains using resting-state functional magnetic resonance imaging (fMRI) in the literature. However, the functional organization of ICNs in macaque brains has been less explored so far, despite growing interests in the field. In this work, we propose a computational framework to identify connectome-scale group-wise consistent ICNs in macaques via sparse representation of whole-brain resting-state fMRI data. Experimental results demonstrate that 70 group-wise consistent ICNs are successfully identified in macaque brains via the proposed framework. These 70 ICNs are interpreted based on two publicly available parcellation maps of macaque brains and our work significantly expand currently known macaque ICNs already reported in the literature. In general, this set of connectome-scale group-wise consistent ICNs can potentially benefit a variety of studies in the neuroscience and brain-mapping fields, and they provide a foundation to better understand brain evolution in the future.Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

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